Esophageal Manifestations of Bullous Pemphigoid

Esophageal Manifestations of Bullous Pemphigoid

Bullous pemphigoid (BP) and mucous membrane pemphigoid (MMP) are autoimmune disorders involving IgG antibodies to basement membrane zone antigens [1]. The natural course of these diseases is that of exacerbations and remissions [2]. Older adults over the age of 60 and men are more likely to be affected [3]. BP manifests as tense, 1-3 cm fluid filled bullae on the skin [2]. The bullae may be on ...

Renal Clinical - Pathological Manifestations in Bullous Pemphigoid

A 61-year old man was admitted with a 2-month history of skin rash, and proteinuria and intermittent hemoptysis for 2 weeks. The patient had developed circular erythema and blisters all over the body with scab formation. Edema of the legs and eyelids appeared 2 weeks prior to admission. Kidney biopsy showed membranous nephropathy (phase II) with focal segmental mesangial proliferation and depos...

Bullous pemphigoid

Bullous pemphigoid

Disease summary: Bullous Pemphigoid is an acquired, chronic, blistering autoimmune subepidermal bullous disease in which autoantibodies are directed against component of basement membrane zone of the skin [1]. It is characterized by formation of cutaneous bullae on the skin and mucous membrane. The pathogenesis involves migration of inflammatory cells into subepithilial tissues due to activatio...

Bullous pemphigoid.

B ullous pemphigoid is an autoimmune disease, which means that the cells in the body that normally fight infection attack the body instead. The body’s immune system is confused and makes an antibody (type of protein used to fight infection) that targets a part of the skin that normally holds it together. The attack on the skin causes blisters (firm, fluid-filled bubbles on the skin) to form. Th...